3.4.24.44: atrolysin E

This is an abbreviated version, for detailed information about atrolysin E, go to the full flat file.

Reaction

Cleavage of Asn3-/-Gln, Ser9-/-His and Ala14-/-Leu bonds in insulin B chain and Tyr14-/-Gln and Thr8-/-Ser in A chain. Cleaves type IV collagen at Ala73-/-Gln in alpha1(IV) and at Gly7-/-Leu in alpha2(IV) =

Synonyms

atrolysin E/D, Crotalus atrox metalloendopeptidase e, Hemorrhagic toxin e, HT-e

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.44 atrolysin E