3.4.24.41: atrolysin B
This is an abbreviated version!
For detailed information about atrolysin B, go to the full flat file.
Word Map on EC 3.4.24.41
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3.4.24.41
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neurotoxin
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seizure-induced
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botulism
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intrahippocampal
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kainic-acid-induced
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bonts
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epilepticus
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kainic
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serotype
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medicine
Reaction
Cleavage of His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Gly23-/-Phe of insulin B chain; identical to the cleavage of insulin B chain by atrolysin C. Also cleaves -/-Ser bonds in glucagon
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Synonyms
Crotalus atrox metalloendopeptidase b, Hemorrhagic toxin b, hemorrhagic toxin b metalloproteinase, HT-b
ECTree
Turnover Number
Turnover Number on EC 3.4.24.41 - atrolysin B
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0.0267 - 1.02
oxidized insulin B-chain
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0.0267
oxidized insulin B-chain
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Gly23-Phe24 bond
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0.0317
oxidized insulin B-chain
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His5-Leu6 bond
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0.132
oxidized insulin B-chain
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His10-Leu11 bond
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0.803
oxidized insulin B-chain
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Ala14-Leu15 bond
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1.02
oxidized insulin B-chain
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Tyr16-Leu17 bond
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