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3.4.24.41: atrolysin B

This is an abbreviated version!
For detailed information about atrolysin B, go to the full flat file.

Word Map on EC 3.4.24.41

Reaction

Cleavage of His5-/-Leu, His10-/-Leu, Ala14-/-Leu, Tyr16-/-Leu and Gly23-/-Phe of insulin B chain; identical to the cleavage of insulin B chain by atrolysin C. Also cleaves -/-Ser bonds in glucagon =

Synonyms

Crotalus atrox metalloendopeptidase b, Hemorrhagic toxin b, hemorrhagic toxin b metalloproteinase, HT-b

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.41 atrolysin B

Reference

Reference on EC 3.4.24.41 - atrolysin B

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fox, J.W.; Bjarnason, J.B.
Atrolysins: metalloproteinases from Crotalus atrox venom
Methods Enzymol.
248
368-387
1995
Crotalus atrox
Manually annotated by BRENDA team
Bjarnason, J.B.; Hamilton, D.; Fox, J.W.
Studies on the mechanism of hemorrhage production by five proteolytic hemorrhagic toxins from Crotalus atrox venom
Biol. Chem. Hoppe-Seyler
369
121-129
1988
Crotalus atrox
Manually annotated by BRENDA team
Bjarnason, J.B.; Tu, A.T.
Hemorrhagic toxins from Western diamondback rattlesnake (Crotalus atrox) venom: isolation and characterization of five toxins and the role of zinc in hemorrhagic toxin e
Biochemistry
17
3395-3404
1978
Crotalus atrox
Manually annotated by BRENDA team
Fox, J.W.; Bjarnason, J.B.
Atrolysin B
Handbook Of Proteolytic Enzymes(Barrett,A. J. ,Rawlings,N. D. ,Woessner,J. F. ,Eds. )Academic Press
1
670-671
2004
Crotalus atrox
-
Manually annotated by BRENDA team
Aung, H.T.; Nikai, T.; Niwa, M.; Takaya, Y.
Rosmarinic acid in Argusia argentea inhibits snake venom-induced hemorrhage
J. Nat. Med.
64
482-486
2010
Crotalus atrox
Manually annotated by BRENDA team