3.4.24.35: gelatinase B

This is an abbreviated version!
For detailed information about gelatinase B, go to the full flat file.

Word Map on EC 3.4.24.35

3.4.24.35

mmp-2

metalloproteinases

zymography

metastasis

timp-1

endothelial

necrosis

angiogenesis

tnf

artery

fibrosis

neutrophil

chemokine

infarct

plaque

monocyte

vessel

pulmonary

myocardial

cerebral

mapks

stroke

erk

transwell

basement

aortic

invasiveness

plasminogen

blood-brain

matrigel

bcl-2

nf-kappab

airway

upa

osteoclast

cox-2

fibronectin

aneurysm

c-reactive

mt1-mmp

e-cadherin

coronary

tnf-alpha

angiogenic

atherosclerotic

anti-metastatic

tartrate-resistant

urokinase-type

drug development

diagnostics

elastin

rankl

medicine

Reaction

Cleavage of gelatin types I and V and collagen types IV and V =

Synonyms

92 kDa gelatinase, 92 kDa type IV collagenase, 92 kDa type IV collagenase proMMP-9, 92-kDa Gelatinase, 92-kDa gelatinase B, 92-kDa Type IV collagenase, 95 kDa type IV collagenase/gelatinase, Collagenase IV, Collagenase type IV, gelatinase, gelatinase B, Gelatinase MMP 9, gelatinolytic enzyme, GELB, Macrophage gelatinase, matrix metallopeptidase 9, matrix metallopeptidase 9 gelatinase B, matrix metalloprotease-9, Matrix metalloproteinase 9, matrix metalloproteinase-9, metrix metalloproteinase-9, MMP 9, MMP-9, MMP9, neutrophil collagenase, pro-matrix metalloproteinase-9, progelatinase, Type IV collagen metalloproteinase, Type IV collagenase, Type IV collagenase/gelatinase, Type V collagenase

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.35 gelatinase B

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Results	in table
62	Activating Compound
1074	AA Sequence
56	Application
1	CAS Registry Number
26	Cloned(Commentary)
47862	Disease/ Diagnostics
118	Expression
82	General Information
30	IC50 Value
181	Inhibitors
5	Ki Value [mM]
17	KM Value [mM]
44	Localization
50	Metals/Ions
90	Molecular Weight [Da]
117	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
1088	Organism
51	PDB ID
23	pH Optimum
16	Posttranslational Modification
37	Protein Variants
20	Purification (Commentary)
1	Reaction
1	Reaction Type
304	Reference
1	Renatured (Commentary)
472	Source Tissue
4	Specific Activity [micromol/min/mg]
1	Storage Stability
402	Substrates and Products (Substrate)
31	Subunits
566	Synonyms
28	Temperature Optimum [°C]
18	Turnover Number [1/s]

Sequence

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Sequence on EC 3.4.24.35 - gelatinase B

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P52176 pBLAST

MMP9_BOVIN

Bos taurus

712

79088

Swiss-Prot