3.4.24.26: pseudolysin
This is an abbreviated version!
For detailed information about pseudolysin, go to the full flat file.
Word Map on EC 3.4.24.26
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3.4.24.26
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thermolysin
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metalloproteinases
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collagenase
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metalloprotease
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3.4.24.4
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elastin
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gelatinase
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elastases
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phosphoramidon
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pseudomonal
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stromelysin
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thermolysin-like
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metalloendopeptidase
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medicine
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thermoproteolyticus
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aureolysin
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vibriolysin
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intrastromal
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industry
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nutrition
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biotechnology
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synthesis
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pharmacology
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diagnostics
- 3.4.24.26
- thermolysin
- metalloproteinases
- collagenase
- metalloprotease
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3.4.24.4
- elastin
- gelatinase
- elastases
- phosphoramidon
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pseudomonal
- stromelysin
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thermolysin-like
- metalloendopeptidase
- medicine
- thermoproteolyticus
- aureolysin
- vibriolysin
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intrastromal
- industry
- nutrition
- biotechnology
- synthesis
- pharmacology
- diagnostics
Reaction
Hydrolysis of proteins including elastin, collagen types III and IV, fibronectin and immunoglobulin A, generally with bulky hydrophobic group at P1'. Insulin B chain cleavage pattern identical to that of thermolysin, but specificity differs in other respects =
Synonyms
A2 elastase, aeruginolysin, ealastase LasB, EC 3.4.24.4, elastase, elastase B, elastolytic metalloproteinase, EPa, LasB, LasB protease, LepA, More, Neutral metalloproteinase, PAE, PASP, PE, PsE, Pseudomonas aeruginosa elastase, Pseudomonas aeruginosa neutral metalloproteinase, Pseudomonas aeruginosa small protease, Pseudomonas elastase, Pseudomonas protease
ECTree
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Organic Solvent Stability
Organic Solvent Stability on EC 3.4.24.26 - pseudolysin
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2-propanol
Acetone
chloroform
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pH 7.0, 30°C, 4 days, 95.6% activity remaining for the nonglycosylated recombinant enzyme, 91.5% for the glycosylated recombinant enzyme
dimethyl sulfoxide
DMSO
Ethanol
Ethyl acetate
hexane
isopropanol
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pH 7.0, 30°C, 4 days, 39.2% activity remaining for the nonglycosylated recombinant enzyme, 17.5% for the glycosylated recombinant enzyme
Methanol
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pH 7.0, 30°C, 4 days, 102% activity remaining for the nonglycosylated recombinant enzyme, 96.5% for the glycosylated recombinant enzyme
n-Butanol
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pH 7.0, 30°C, 4 days, 89.5% activity remaining for the nonglycosylated recombinant enzyme, 78.5% for the glycosylated recombinant enzyme
additional information
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pH 7.0, 30°C, 4 days, 95.1% activity remaining for the nonglycosylated recombinant enzyme, 83.2% for the glycosylated recombinant enzyme
Ethanol
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pH 7.0, 30°C, 4 days, 71.5% activity remaining for the nonglycosylated recombinant enzyme, 62.1% for the glycosylated recombinant enzyme
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the enzyme is stable in the presence of organic solvents mainly diethyl ether and DMSO
additional information
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the enzyme is stable in the presence of organic solvents mainly diethyl ether and DMSO
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