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3.4.24.24: gelatinase A

This is an abbreviated version!
For detailed information about gelatinase A, go to the full flat file.

Word Map on EC 3.4.24.24

Reaction

Cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-/-Ile-Ala-Gly-Gln =

Synonyms

72 kDa Gelatinase, 72 kDa Gelatinase type A, 72 kDa type IV collagenase, 72-kDa Gelatinase, Collagenase IV, Collagenase type IV, GelA, gelatinase, gelatinase A, human gelatinase A, human matrix metalloproteinase 2, human matrix metalloproteinase-2, LvMMP-2, matrix metallopeptidase 2, matrix metalloprotease 2, Matrix metalloproteinase 2, matrix metalloproteinase-2, matrix metalloprotenase-2, metalloproteinase-2, metrix metalloproteinase-2, MMP 2, MMP-2, MMP2, progelatinase, Type IV collagen metalloproteinase, Type IV collagenase, Type IV collagenase/gelatinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.24 gelatinase A

Natural Substrates Products

Natural Substrates Products on EC 3.4.24.24 - gelatinase A

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Collagen + H2O
?
show the reaction diagram
collagen type IV + H2O
?
show the reaction diagram
-
-
-
-
?
collagene type IV + H2O
?
show the reaction diagram
-
-
-
-
?
extracellular matrix components + H2O
?
show the reaction diagram
-
-
?
Fibrinogen + H2O
?
show the reaction diagram
-
-
-
-
?
Gelatin + H2O
?
show the reaction diagram
Type I collagen + H2O
?
show the reaction diagram
degradation
-
-
?
Type IV collagen + H2O
?
show the reaction diagram
additional information
?
-