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3.4.24.21: astacin

This is an abbreviated version!
For detailed information about astacin, go to the full flat file.

Word Map on EC 3.4.24.21

Reaction

Hydrolysis of peptide bonds in substrates containing five or additional information amino acids, preferentially with Ala in P1', and Pro in P2' =

Synonyms

Ace-MTP-2, Ancylostoma ceylanicum metalloprotease 2, Ast1, Ast2, Ast3, Ast4, Ast5, Ast6, Ast7, Ast9, astacin, astacin metallopeptidases, astacin metalloprotease, astacin-like metalloendopeptidase, astacin-like metalloprotease, astacin-like metalloprotease toxin 3, astacin-Like protease 3, Astacus protease, Astacus proteinase, ASTL, BMP-1, bone morphogenetic protein 1, carp nephrosin, crayfish small-molecule protease, Crayfish small-molecule proteinase, DPY-31, EC 3.4.99.6, LALP3, LAST, LAST_MAM, MEP1A, MEP1B, More, NAS-35, nas-36, nas-37, nephrosin, Ovastacin, Procollagen C-proteinase, Qcam1, Sc-AST, Smed-ast-1, Smed-ast-2, Smed-ast-3, Smed-ast-4, Smed-ast-5, Smed-ast-6, Smed-ast-7, Smed-ast-9, toxin 3, Xhe2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.21 astacin

KM Value

KM Value on EC 3.4.24.21 - astacin

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.327
2-Aminobenzoyl-Arg-Gly-Pro-Phe-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.044
2-Aminobenzoyl-Arg-Hyp-Gly-Phe-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.154
2-Aminobenzoyl-Arg-Pro-Gly-Ala-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.954
2-Aminobenzoyl-Arg-Pro-Gly-Glu-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.867 - 0.87
2-Aminobenzoyl-Arg-Pro-Gly-Leu-Ser-Pro-(4-nitro)Phe-Arg
0.281
2-Aminobenzoyl-Arg-Pro-Gly-Lys-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.029
2-Aminobenzoyl-Arg-Pro-Ile-Phe-Ser-Pro-(4-nitro)Phe-Arg
-
-
0.306
Arg-Pro-Pro-Gly-(4-nitro)Phe-Ala-Pro-Phe-Arg
-
-
0.209
Arg-Pro-Pro-Gly-(4-nitro)Phe-Arg-Pro-Phe-Arg
-
-
0.116
Arg-Pro-Pro-Gly-(4-nitro)Phe-Lys-Pro-Phe-Arg
-
-
0.194
Arg-Pro-Pro-Gly-(4-nitro)Phe-Phe-Pro-Phe-Arg
-
-
0.085
Arg-Pro-Pro-Gly-(4-nitro)Phe-Ser-Pro-Phe-Arg
-
-
1.86
azocasein
pH 7.5, 37°C, Vmax: 0.281 microM/min
-
0.48
Dansyl-Ala-Ala-Arg-Ala-Pro-Leu-Val
-
-
56
Dansyl-Arg-Ala-Pro-Leu
-
-
0.39
Dansyl-Gly-Arg-Arg-Ala-Pro-Leu-Gly
-
-
5
Dansyl-Gly-Gly-Arg-Ala-Pro-Trp-Val
-
-
0.017
Dansyl-Gly-Lys-Arg-Ala-Pro-Leu-Val
-
-
0.015
Dansyl-Gly-Lys-Arg-Ala-Pro-Trp-Val
-
-
0.4 - 0.52
Dansyl-Gly-Lys-Asn-Ala-Pro-Leu-Val
0.27
Dansyl-Gly-Lys-Tyr-Ala-Pro-Trp-Val
-
-
0.53
Dansyl-Gly-Pro-Arg-Ala-Pro-Leu-Val
-
-
0.23
Dansyl-His-His-Leu-Lys-Arg-Ala-Pro-Trp-Val
-
dansyl-Gly-Arg-Arg-Ala-Ser-Leu-Gly
0.58
Dansyl-Leu-Arg-Arg-Ala-Pro-Leu-Gly
-
-
0.67
Dansyl-Leu-Arg-Arg-Ala-Ser-Leu-Gly
-
-
0.33
Dansyl-Leu-Lys-Arg-Ala-Pro-Trp-Val
-
-
1
Dansyl-Leu-Lys-Asn-Ala-Pro-Leu-Val
-
-
0.29
Dansyl-Leu-Lys-Lys-Ala-Pro-Trp-Val
-
-
0.28
Dansyl-Leu-Lys-Tyr-Ala-Pro-Trp-Val
-
-
2
Dansyl-Lys-Arg-Ala-Pro-Leu
-
-
0.37
Dansyl-Pro-Lys-Arg-Ala-Pro-Trp-Val
-
-
0.25
Dansyl-Val-Lys-Arg-Ala-Pro-Trp-Val
-
dansyl-Leu-Lys-Arg-Ala-Pro-Leu-Val