3.4.24.18: meprin A

This is an abbreviated version!
For detailed information about meprin A, go to the full flat file.

Word Map on EC 3.4.24.18

3.4.24.18

3.4.24.11

enkephalinase

metalloendopeptidase

atrial

phosphoramidon

natriuretic

enkephalin

thiorphan

angiotensin-converting

angiotensin

astacins

metalloproteases

brush

bradykinin

3.4.15.1

captopril

neprilysin

metallopeptidases

anp

aminopeptidases

acetorphan

math

endopeptidases

brush-border

microvillar

actinonin

calla

bestatin

amastatin

azocasein

phosphoramidon-sensitive

sheddase

dipeptidylaminopeptidase

metzincins

pharmacology

neurokinins

astacin-like

met5enkephalin

depressor

medicine

tachykinins

neurotensin

leu-enkephalin

Reaction

Hydrolysis of protein and peptide substrates preferentially on carboxyl side of hydrophobic residues =

Synonyms

E-24.18, EC 3.4.24.11, Endopeptidase-2, M12.002, MEP1A, Meprin, meprin A, meprin A metalloprotease, meprin A metalloproteinase, meprin A subunit alpha, meprin alpha, meprin alpha1, meprin alpha2, meprin beta, meprin metalloprotease, meprin metalloproteinase, Meprin-a, meprin-alpha, metalloprotease meprin A, metalloproteinase meprin alpha, Mmepa, More, mouse meprin alpha, N-Benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase, PABA peptide hydrolase, PABA-peptide hydrolase, PPH, PPH alpha, PPH beta, procollagen proteinase, Rmepa

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.18 meprin A

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Results	in table
12	Activating Compound
15	AA Sequence
11	Application
1	CAS Registry Number
28	Cloned(Commentary)
642	Disease/ Diagnostics
2	Expression
63	General Information
1	General Stability
27	IC50 Value
144	Inhibitors
2	kcat/KM [mM/s]
20	Ki Value [mM]
56	KM Value [mM]
66	Localization
62	Metals/Ions
63	Molecular Weight [Da]
88	Natural Substrates/ Products (Substrates)
317	Organism
14	PDB ID
18	pH Optimum
3	pH Range
2	pH Stability
30	Posttranslational Modification
24	Protein Variants
25	Purification (Commentary)
1	Reaction
3	Reaction Type
90	Reference
125	Source Tissue
29	Specific Activity [micromol/min/mg]
3	Storage Stability
373	Substrates and Products (Substrate)
56	Subunits
65	Synonyms
23	Temperature Optimum [°C]
4	Temperature Stability [°C]
52	Turnover Number [1/s]

Organism

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Organism on EC 3.4.24.18 - meprin A

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Canis lupus familiaris

697872, 733065

Canis lupus familiaris Madin-Darby

PPH

31021, 31022, 31027, 31031, 31032

Mus musculus C57BL/6N

733064

Mus musculus C57BL6

734296

Mus musculus male ICR

male ICR

31024

Rattus norvegicus

8 entries