3.4.24.17: stromelysin 1

This is an abbreviated version!
For detailed information about stromelysin 1, go to the full flat file.

Word Map on EC 3.4.24.17

3.4.24.17

metalloproteinases

mmp-1

cartilage

arthritis

joint

osteoarthritis

rheumatoid

synovial

chondrocytes

necrosis

timps

articular

gelatinase

tnf

interleukin-1

knee

zymography

degeneration

aggrecan

proteoglycans

c-reactive

interstitial

gelatin

plasminogen

proteinases

cox-2

synoviocytes

il-1beta

fibroblast-like

cruciate

intervertebral

ligament

matrilysin

pulposus

matrix-degrading

adamts-4

synovitis

thrombospondin

intra-articular

subchondral

emmprin

chondroprotective

photoaging

collagenases

diagnostics

medicine

aggrecanase

prommp-9

neoepitope

gelatinolytic

mt1-mmp

collagenolytic

drug development

analysis

Reaction

preferential cleavage where P1', P2' and P3' are hydrophobic residues =

Synonyms

Collagen-activating protein, Collagenase activating protein, matrix metalloprotease-3, Matrix metalloproteinase 3, matrix metalloproteinase-3, matrixin, MMP-3, MMP3, Neutral proteoglycanase, Procollagenase activator, Proteoglycanase, PTR1 protein, ST1, Stromelysin, stromelysin-1, Transin

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.17 stromelysin 1

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
8	Activating Compound
15	AA Sequence
22	Application
1	CAS Registry Number
11	Cloned(Commentary)
5	Crystallization (Commentary)
7657	Disease/ Diagnostics
22	Expression
30	General Information
4	General Stability
42	IC50 Value
273	Inhibitors
6	kcat/KM [mM/s]
76	Ki Value [mM]
11	KM Value [mM]
25	Localization
35	Metals/Ions
12	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
105	Organism
70	PDB ID
15	pH Optimum
3	pH Range
11	pH Stability
2	Posttranslational Modification
14	Protein Variants
19	Purification (Commentary)
1	Reaction
1	Reaction Type
98	Reference
88	Source Tissue
12	Specific Activity [micromol/min/mg]
5	Storage Stability
142	Substrates and Products (Substrate)
7	Subunits
109	Synonyms
12	Temperature Optimum [°C]
5	Temperature Stability [°C]
10	Turnover Number [1/s]

Localization

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Localization on EC 3.4.24.17 - stromelysin 1

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Localization Search

cytoplasm

Homo sapiens

P08254

the enzyme moves from cytoplasm to cell nucleus upon Dengue virus infection and colocalizes with NFkappaB P65 in the nucleus

the enzyme moves from cytoplasm to cell nucleus upon Dengue virus infection and colocalizes with NFkappaB P65 in the nucleus

5634

735131

additional information

Homo sapiens

invasive trophoblast cell models secrete bioactive MMP-3

710257