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3.4.24.17: stromelysin 1

This is an abbreviated version!
For detailed information about stromelysin 1, go to the full flat file.

Word Map on EC 3.4.24.17

Reaction

preferential cleavage where P1', P2' and P3' are hydrophobic residues =

Synonyms

Collagen-activating protein, Collagenase activating protein, matrix metalloprotease-3, Matrix metalloproteinase 3, matrix metalloproteinase-3, matrixin, MMP-3, MMP3, Neutral proteoglycanase, Procollagenase activator, Proteoglycanase, PTR1 protein, ST1, Stromelysin, stromelysin-1, Transin

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.17 stromelysin 1

Activating Compound

Activating Compound on EC 3.4.24.17 - stromelysin 1

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
beta-hematin
-
induces differential autocatalysis of the propeptide
cytosolic protein Apaf-1
-
-
hemin
-
induces differential autocatalysis of the propeptide
p-aminophenylmercuric acetate
-
i.e. APMA, initiates an MMP-3 autocatalytic mechanism by disturbing the interaction of zinc with a critical cysteine residue
plasmin
-
-
-
Trypsin
-
-
-
additional information
-