3.4.23.B9: bovine leukemia virus protease
This is an abbreviated version!
For detailed information about bovine leukemia virus protease, go to the full flat file.
Reaction
The best substrate YDPPAILPII is bearing the natural cleavage site between the matrix and the capsid proteins of BLV Gag precursor. polyprotein. Good cleavage of the peptide bonds: Leu-Pro, Leu-Val, Gly-Val and Leu-Pro
=
Synonyms
BLV endopeptidase, BLV PR, BLV protease, bovine leukemia virus protease, bovine leukemia virus retropepsin, BVL PR, More
ECTree
Inhibitors
Inhibitors on EC 3.4.23.B9 - bovine leukemia virus protease
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Ac-PQVL-azetidine-VM
-
IC50: 0.25 mM
Ac-PQVL-pipecolic acid-VM
-
IC50: 0.015 mM
Ac-Pro-Glu-Val-Leu-azetidine-Val-Met
-
IC50: 0.250 mM
Ac-Pro-Glu-Val-Leu-pipecolic acid-Val-Met
-
IC50: 0.015 mM
Ala-Pro-Gln-Val-Leu-r-Pro-Val-Met-His-Pro
-
Ala-Pro-Gln-Val-Sta-Val-Met-His-Pro
-
Gly-Val-Leu-Tyr-statine-Glu-Ala
-
IC50: 0.10 mM
HBY-793
a compound which inhibits EIAV PR
KH 164
modest inhibitor of MMLV PR
LP-149
inhibitor of FIV PR
Lys-Thr-Lys-Val-Leu-r-Val-Val-Gln-Pro-Lys
-
Lys-Thr-Lys-Val-Sta-Val-Gln-Pro-Gly
-
pepstatin A
-
IC50: 0.3-0.5 mM
PQV-statine-AI
-
IC50: 0.1 mM
Pro-Glu-Val-statine-Ala-Leu
-
IC50: 0.10 mM
UK 88.947
a compound which inhibits HIV-1PR
YDPPAI-statine-II
-
IC50: 0.0005 mM
YDPPAI-statine-II
-
strong inhibition, IC50: 0.0005 mM