3.4.23.B6: Mason-Pfizer monkey virus proteinase

This is an abbreviated version!
For detailed information about Mason-Pfizer monkey virus proteinase, go to the full flat file.

Word Map on EC 3.4.23.B6

3.4.23.B6

retroviral

polyproteins

capsid

virion

retropepsins

flap

g-patch

d-type

retroviruses

glycine-rich

gag-related

pepsin-like

Reaction

The enzyme cleaves 17 amino acids of the C-terminal 38-amino-acid cytoplasmic tail of the transmembrane protein TM of the released immature virus. =

Synonyms

M-PMV PR, M-PMV protease, Mason-Pfizer leukemia virus retropepsin, Mason-Pfizer monkey virus retropepsin, More, MPMV protease, P-MPV poteinase, P-MPV PR

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.B6 Mason-Pfizer monkey virus proteinase

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Results	in table
2	Activating Compound
1	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
2	Crystallization (Commentary)
9	Inhibitors
7	Ki Value [mM]
15	KM Value [mM]
1	Localization
3	Metals/Ions
12	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
19	Organism
6	pH Optimum
1	pH Stability
3	pI Value
5	Posttranslational Modification
11	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
19	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
3	Storage Stability
54	Substrates and Products (Substrate)
6	Subunits
15	Synonyms
3	Temperature Optimum [°C]
13	Turnover Number [1/s]

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Turnover Number on EC 3.4.23.B6 - Mason-Pfizer monkey virus proteinase

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4.65

APTVMAVVNP

Mason-Pfizer monkey virus

pH 5.3, 37°C

646011

0.1 - 7

ATPQVYF(NO2)VRKA

5 entries

0.053 - 0.43

IQVHYHRLEQ

3 entries

7.6

PKDIFPVTET

Mason-Pfizer monkey virus

pH 5.3, 37°C

646011

7.7

PKQAYGAVFV

Mason-Pfizer monkey virus

pH 5.3, 37°C

646011

4.56

SSDIYWVQPI

Mason-Pfizer monkey virus

pH 5.3, 37°C

646011

additional information

Mason-Pfizer monkey virus

turnover-numbers for peptide substrates spanning the processing sites within the M-PMV Gag, Gag-Pro and Env polyproteins

646015