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3.4.23.B6: Mason-Pfizer monkey virus proteinase

This is an abbreviated version!
For detailed information about Mason-Pfizer monkey virus proteinase, go to the full flat file.

Word Map on EC 3.4.23.B6

Reaction

The enzyme cleaves 17 amino acids of the C-terminal 38-amino-acid cytoplasmic tail of the transmembrane protein TM of the released immature virus. =

Synonyms

M-PMV PR, M-PMV protease, Mason-Pfizer leukemia virus retropepsin, Mason-Pfizer monkey virus retropepsin, More, MPMV protease, P-MPV poteinase, P-MPV PR

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.B6 Mason-Pfizer monkey virus proteinase

Reference

Reference on EC 3.4.23.B6 - Mason-Pfizer monkey virus proteinase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Sonigo, P.; Barker, C.; Hunter, E.; Wain-Hobson, S.
Nucleotide sequence of Mason-Pfizer monkey virus: an immunosuppressive D-type retrovirus
Cell
45
375-385
1986
Mason-Pfizer monkey virus (P07570)
Manually annotated by BRENDA team
Rumlova, M.; Ruml, T.; Pohl, J.; Pichova, I.
Specific in vitro cleavage of Mason-Pfizer monkey virus capsid protein: evidence for a potential role of retroviral protease in early stages of infection
Virology
310
310-318
2003
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Snasel, J.; Shoeman, R.; Horejsi, M.; Hruskova-Heidingsfeldova, O.; Sedlacek, J.; Ruml, T.; Pichova, I.
Cleavage of vimentin by different retroviral proteases
Arch. Biochem. Biophys.
377
241-245
2000
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Zabransky, A.; Andreansky, M.; Hruskova-Heidingsfeldova, O.; Havlicek, V.; Hunter, E.; Ruml, T.; Pichova, I.
Three active forms of aspartic proteinase from Mason-Pfizer monkey virus
Virology
245
250-256
1998
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Hruskova-Heidingsfeldova, O.; Andreansky, M.; Fabry, M.; Blaha, I.; Strop, P.; Hunter, E.
Cloning, bacterial expression, and characterization of the Mason-Pfizer monkey virus proteinase
J. Biol. Chem.
270
15053-15058
1995
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Brody, B.A.; Rhee, S.S.; Sommerfelt, M.A.; Hunter, E.
A viral protease-mediated cleavage of the transmembrane glycoprotein of Mason-Pfizer monkey virus can be suppressed by mutations within the matrix protein
Proc. Natl. Acad. Sci. USA
89
3443-3447
1992
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Sommerfelt, M.A.; Petteway, S.R., Jr.; Dreyer, G.B.; Hunter, E.
Effect of retroviral proteinase inhibitors on Mason-Pfizer monkey virus maturation and transmembrane glycoprotein cleavage
J. Virol.
66
4220-4227
1992
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Parker, S.D.; Hunter, E.
Activation of the Mason-Pfizer monkey virus protease within immature capsids in vitro
Proc. Natl. Acad. Sci. USA
98
14631-14636
2001
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Pichova, I.; Zabransky, A.; Kost'alova, I.; Hruskova-Heidingsfeldova, O.; Andreansky, M.; Hunter, E.; Ruml, T.
Analysis of autoprocessing of Mason-Pfizer monkey virus proteinase in vitro. Three active forms of proteinase
Adv. Exp. Med. Biol.
436
105-108
1998
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Bagossi, P.; Sperka, T.; Feher, A.; Kadas, J.; Zahuczky, G.; Miklossy, G.; Boross, P.; Toezser, J.
Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites
J. Virol.
79
4213-4218
2005
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Pichova, I.
Mason-Pfizer monkey virus retropepsin
Handbook of Proteolytic Enzymes (Barrett, J. ; Rawlings, N. D. ; Woessner, J. F. , eds. )
1
172-174
2004
Mason-Pfizer monkey virus
-
Manually annotated by BRENDA team
Bauerova-Zabranska, H.; Stokrova, J.; Strisovsky, K.; Hunter, E.; Ruml, T.; Pichova, I.
The RNA binding G-patch domain in retroviral protease is important for infectivity and D-type morphogenesis of Mason-Pfizer monkey virus
J. Biol. Chem.
280
42106-42112
2005
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Song, C.; Micoli, K.; Bauerova, H.; Pichova, I.; Hunter, E.
Amino acid residues in the cytoplasmic domain of the Mason-Pfizer monkey virus glycoprotein critical for its incorporation into virions
J. Virol.
79
11559-11568
2005
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Song, C.; Micoli, K.; Hunter, E.
Activity of the Mason-Pfizer monkey virus fusion protein is modulated by single amino acids in the cytoplasmic tail
J. Virol.
79
11569-11579
2005
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Zábranská, H.; Tuma, R.; Kluh, I.; Svatoš, A.; Ruml, T.; Hrabal, R.; Pichová, I.
The role of the S-S bridge in retroviral protease function and virion maturation
J. Mol. Biol.
365
1493-1504
2007
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Veverka, V.; Bauerova, H.; Zabransky, A.; Lang, J.; Ruml, T.; Pichova, I.; Hrabal, R.
Three-dimensional structure of a monomeric form of a retroviral protease
J. Mol. Biol.
333
771-780
2003
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Eizert, H.; Bander, P.; Bagossi, P.; Sperka, T.; Miklossy, G.; Boross, P.; Weber, I.T.; Toezser, J.
Amino acid preferences of retroviral proteases for amino-terminal positions in a type 1 cleavage site
J. Virol.
82
10111-10117
2008
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Macek, P.; Chmelik, J.; Krizova, I.; Kaderavek, P.; Padrta, P.; Zidek, L.; Wildova, M.; Hadravova, R.; Chaloupkova, R.; Pichova, I.; Ruml, T.; Rumlova, M.; Sklenar, V.
NMR structure of the N-terminal domain of capsid protein from the Mason-Pfizer monkey virus
J. Mol. Biol.
392
100-114
2009
Mason-Pfizer monkey virus
Manually annotated by BRENDA team
Yoshikawa, R.; Takeuchi, J.S.; Yamada, E.; Nakano, Y.; Misawa, N.; Kimura, Y.; Ren, F.; Miyazawa, T.; Koyanagi, Y.; Sato, K.
Feline immunodeficiency virus evolutionarily acquires two proteins, Vif and protease, capable of antagonizing feline APOBEC3
J. Virol.
91
e00250-17
2017
feline immunodeficiency virus
Manually annotated by BRENDA team