3.4.23.B6: Mason-Pfizer monkey virus proteinase

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For detailed information about Mason-Pfizer monkey virus proteinase, go to the full flat file.

Reaction

The enzyme cleaves 17 amino acids of the C-terminal 38-amino-acid cytoplasmic tail of the transmembrane protein TM of the released immature virus. =

Synonyms

M-PMV PR, M-PMV protease, Mason-Pfizer leukemia virus retropepsin, Mason-Pfizer monkey virus retropepsin, More, MPMV protease, P-MPV poteinase, P-MPV PR

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.B6 Mason-Pfizer monkey virus proteinase

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Results	in table
2	Activating Compound
1	AA Sequence
1	CAS Registry Number
7	Cloned(Commentary)
2	Crystallization (Commentary)
9	Inhibitors
7	Ki Value [mM]
15	KM Value [mM]
1	Localization
3	Metals/Ions
12	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
19	Organism
6	pH Optimum
1	pH Stability
3	pI Value
5	Posttranslational Modification
11	Protein Variants
6	Purification (Commentary)
1	Reaction
1	Reaction Type
19	Reference
1	Source Tissue
1	Specific Activity [micromol/min/mg]
3	Storage Stability
54	Substrates and Products (Substrate)
6	Subunits
15	Synonyms
3	Temperature Optimum [°C]
13	Turnover Number [1/s]

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Cloned on EC 3.4.23.B6 - Mason-Pfizer monkey virus proteinase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

cloning and expression of the 3'-region of the Mason-Pfizer monkey virus pro gene in Escherichia coli

Mason-Pfizer monkey virus

-

646011

expressed in Escherichia coli BL21(DE3) cells

Mason-Pfizer monkey virus

-

712745

expression in Escherichia coli BL21

Mason-Pfizer monkey virus

-

681478

expression in Escherichia coli in inclusion bodies

Mason-Pfizer monkey virus

-

668797

expression of wild-type and mutant enzymes in COS-1 cells

Mason-Pfizer monkey virus

-

670079

expression of wild-type and mutant enzymes in Escherichia coli strain BL21(DE3)

Mason-Pfizer monkey virus

-

669413

phylogenetic tree

Mason-Pfizer monkey virus

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666190