3.4.23.B24: signal peptide peptidase

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For detailed information about signal peptide peptidase, go to the full flat file.

Reaction

intramembrane cleavage of signal peptides =

Synonyms

ANID_08681, aspartic intramembrane protease, Hm13, hSPP, minor histocompatibility antigen H13, PF3D7_1457000, PlSPP, signal peptide peptidase like 2a, signal peptide peptidase-like 2a, signal peptide peptidase-like 2B, signal peptide peptidase-like 2C, signal peptide peptidase-like 3, SPP, SPP-like 2A, SPP-like 2B, SPP-like 2C, SPP-like 3, SPP1, SppA, SPPL, SPPL2a, SPPL2b, SPPL2c, UMAG_02729

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.B24 signal peptide peptidase

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Results	in table
13	AA Sequence
12	Application
16	Cloned(Commentary)
2	Crystallization (Commentary)
117	Disease/ Diagnostics
4	Expression
46	General Information
31	IC50 Value
64	Inhibitors
1	Ki Value [mM]
1	KM Value [mM]
19	Localization
8	Molecular Weight [Da]
20	Natural Substrates/ Products (Substrates)
41	Organism
1	pH Optimum
27	Protein Variants
1	Reaction
36	Reference
49	Source Tissue
57	Substrates and Products (Substrate)
17	Subunits
65	Synonyms
1	Temperature Optimum [°C]
1	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.078

dodecanoyl-NGEVAKA-4-methylcumaryl-7-amide

Bacillus subtilis

O34525

pH 8.0, 23°C

733343