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3.4.23.B13: proteinase P15

This is an abbreviated version!
For detailed information about proteinase P15, go to the full flat file.

Word Map on EC 3.4.23.B13

Reaction

efficient cleavage of Ala-Thr-His-Glu-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala, no cleavage with Ser, Arg or Glu at P1, Gly or Phe at P2, and Pro at P3. Specifically liberates the five major structural proteins from the common gag precursor, as well as reverse transcriptase and integrase from the gag-pol precursor =

Synonyms

15gag proteinase, MAV-PR, myeloblastosis associated virus proteinase, p15gag proteinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.B13 proteinase P15

KM Value

KM Value on EC 3.4.23.B13 - proteinase P15

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.004 - 0.024
Ala-Thr-His-Arg-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.017
Ala-Thr-His-Asn-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
pH 6.0, 37°C
0.007 - 0.025
Ala-Thr-His-Asp-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.007 - 0.009
Ala-Thr-His-Gln-Ala-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.007 - 0.042
Ala-Thr-His-Gln-Ile-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.025 - 0.12
Ala-Thr-His-Gln-Leu-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.052
Ala-Thr-His-Gln-Val-Leu-Phe(NO2)-Val-Arg-Lys-Ala
pH 6.0, 37°C
0.013 - 0.031
Ala-Thr-His-Gln-Val-Phe-Phe(NO2)-Val-Arg-Lys-Ala
0.007 - 0.082
Ala-Thr-His-Gln-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.003 - 0.0062
Ala-Thr-His-Glu-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.0016 - 0.026
Ala-Thr-His-Tyr-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
0.014
Ala-Thr-His-Val-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
pH 6.0, 37°C
0.008
Ala-Thr-Pro-Cys-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
pH 6.0, 37°C
0.009
Ala-Thr-Pro-Gln-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
pH 6.0, 37°C