3.4.23.B1: napsin

This is an abbreviated version!
For detailed information about napsin, go to the full flat file.

Word Map on EC 3.4.23.B1

3.4.23.B1

adenocarcinoma

thyroid

pulmonary

resect

cytokeratins

non-small

factor-1

papillary

immunophenotype

alk

endometrioid

synaptophysin

chromogranin

adenosquamous

medicine

calretinin

analysis

lepidic

a-positive

diagnostics

immunomarkers

nonpulmonary

sarcomatoid

immunoprofile

amacr

micropapillary

cytopathol

mammaglobin

mucicarmine

Reaction

belongs to the aspartic proteinases =

Synonyms

napsin, napsin A, napsin-A, TA02 protein, TAO2

ECTree

3.4 Acting on peptide bonds (peptidases)

3.4.23 Aspartic endopeptidases

3.4.23.B1 napsin

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Results	in table
3	AA Sequence
21	Application
1	CAS Registry Number
6	Cloned(Commentary)
2092	Disease/ Diagnostics
2	Expression
3	General Information
25	Inhibitors
23	Ki Value [mM]
2	KM Value [mM]
10	Localization
4	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
35	Organism
2	pH Optimum
1	pH Range
4	pH Stability
1	pI Value
3	Posttranslational Modification
3	Purification (Commentary)
6	Reaction
13	Reaction Type
34	Reference
103	Source Tissue
4	Specific Activity [micromol/min/mg]
30	Substrates and Products (Substrate)
4	Subunits
20	Synonyms
2	Temperature Optimum [°C]

KI Value

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KI Value on EC 3.4.23.B1 - napsin

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0.0006

17 kDa protein of Ascaris lumbricoides

pH 4.7, 37°C

-

0.00011

ABT-538

pH 4.7, 37°C

0.00001

Ac-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2

pH 4.7, 37°C

0.00002

ethoxycarbonyl-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2

pH 4.7, 37°C

0.00007

isobutyryl-HPFA-statine-LF-NH2

pH 4.7, 37°C

0.00016

isobutyryl-HPFH-statine-LF-NH2

pH 4.7, 37°C

0.001

isobutyryl-HPFY-statine-LF-NH2

pH 4.7, 37°C

0.000105

isovaleryl-HPF-2-naphthylalanine-statine-LF-NH2

pH 4.7, 37°C

0.000003

isovaleryl-HPF-homophenylalanine-statine-LF-NH2

pH 4.7, 37°C

0.000012

isovaleryl-HPFH-(4-amino-3-hydroxy-5-phenylpentanoic acid)-LF-NH2

pH 4.7, 37°C

0.000065

isovaleryl-HPFH-(4-amino-3-hydroxy-6-methylheptanoic acid)-LF-NH2

pH 4.7, 37°C

0.00014

isovaleryl-HPFH-statine-delta-N-acetylornithine-F-NH2

pH 4.7, 37°C

0.000055

isovaleryl-HPFH-statine-IF-NH2

pH 4.7, 37°C

0.00057

isovaleryl-HPFH-statine-IH-NH2

pH 4.7, 37°C

0.0002

isovaleryl-HPFH-statine-LF-NH2

pH 4.7, 37°C

0.00000015

isovaleryl-pepstatin

pH 4.7, 37°C

-

0.000016

lactoyl-pepstatin

pH 4.7, 37°C

0.000002

pepstatin

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0.003

t-butoxycarbonyl-HPFH-statine-LF-NH2

pH 4.7, 37°C

0.000185

t-butoxycarbonyl-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2

pH 4.7, 37°C

0.000012

t-butoxycarbonyl-Phe-His-statine-Leu-Phe-NH2

pH 4.7, 37°C

0.0005

TLIRIPLHRVQPGRRILNL

pH 4.7, 37°C

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Release 2023.1 (January 2023)