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3.4.23.B1: napsin

This is an abbreviated version!
For detailed information about napsin, go to the full flat file.

Word Map on EC 3.4.23.B1

Reaction

belongs to the aspartic proteinases =

Synonyms

napsin, napsin A, napsin-A, TA02 protein, TAO2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.B1 napsin

Inhibitors

Inhibitors on EC 3.4.23.B1 - napsin

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
17 kDa protein of Ascaris lumbricoides
weak inhibition
-
ABT-538
HIV proteinase inhibitor
Ac-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2
-
ethoxycarbonyl-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2
-
isobutyryl-HPFA-statine-LF-NH2
-
isobutyryl-HPFH-statine-LF-NH2
-
isobutyryl-HPFY-statine-LF-NH2
-
isovaleryl-HPF-2-naphthylalanine-statine-LF-NH2
-
isovaleryl-HPF-homophenylalanine-statine-LF-NH2
-
isovaleryl-HPFH-(4-amino-3-hydroxy-5-phenylpentanoic acid)-LF-NH2
-
isovaleryl-HPFH-(4-amino-3-hydroxy-6-methylheptanoic acid)-LF-NH2
-
isovaleryl-HPFH-statine-delta-N-acetylornithine-F-NH2
-
isovaleryl-HPFH-statine-IF-NH2
-
isovaleryl-HPFH-statine-IH-NH2
-
isovaleryl-HPFH-statine-LF-NH2
-
isovaleryl-pepstatin
strong inhibition
-
lactoyl-pepstatin
strong inhibition
pepstatin
pepstatin A
napsin A binds over a broad pH range to this inhibitor, highly selective binding of napsin A
t-butoxycarbonyl-HPFH-statine-LF-NH2
-
t-butoxycarbonyl-Phe-His-(4-amino-3-hydroxy-6-methylheptanoic acid)-Leu-Phe-NH2
-
t-butoxycarbonyl-Phe-His-statine-Leu-Phe-NH2
-
TLIRIPLHRVQPGRRILNL
biotinylated, derived from residues 1P-19P of the 34 amino acid propart of pronapsin A