3.4.23.51: HycI peptidase

This is an abbreviated version!
For detailed information about HycI peptidase, go to the full flat file.

Reaction

This enzyme specifically removes a 32-amino acid peptide from the C-terminus of the precursor of the large subunit of hydrogenase 3 in Escherichia coli by cleavage at the C-terminal side of Arg537. =

Synonyms

HycE processing protein, HYCI, HycI endopeptidase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.51 HycI peptidase

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Results	in table
1050	AA Sequence
2	Cloned(Commentary)
2	Crystallization (Commentary)
1	Inhibitors
3	Metals/Ions
3	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
8	Organism
1	Pathway
1	pI Value
4	Protein Variants
4	Purification (Commentary)
1	Reaction
8	Reference
12	Substrates and Products (Substrate)
2	Subunits
7	Synonyms

Reference

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Reference on EC 3.4.23.51 - HycI peptidase

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REF.

AUTHORS

TITLE

JOURNAL

VOL.

PAGES

YEAR

ORGANISM (UNIPROT)

PUBMED ID

SOURCE

649503

Theodoratou, E.; Paschos, A.; Mintz-Weber, S.; Bock, A.

Analysis of the cleavage site specificity of the endopeptidase involved in the maturation of the large subunit of hydrogenase 3 from Escherichia coli

Arch. Microbiol.

173

110-116

2000

Escherichia coli (P0AEV9)

10795682

brenda

651066

Theodoratou, E.; Paschos, A.; Magalon, A.; Fritsche, E.; Huber, R.; Bock, A.

Nickel serves as a substrate recognition motif for the endopeptidase involved in hydrogenase maturation

Eur. J. Biochem.

267

1995-1999

2000

Escherichia coli (P0AEV9)

10727938

brenda

680866

Yang, F.; Hu, W.; Xu, H.; Li, C.; Xia, B.; Jin, C.

Solution structure and backbone dynamics of an endopeptidase HycI from Escherichia coli: implications for mechanism of the [NiFe] hydrogenase maturation

J. Biol. Chem.

282

3856-3863

2007

Escherichia coli (P0AEV9)

17150961

brenda

690862

Theodoratou, E.; Huber, R.; B�ck A.

[NiFe]-Hydrogenase maturation endopeptidase: structure and function

Biochem. Soc. Trans.

33

108-111

2005

Escherichia coli (P0AEV9)

15667279

brenda

690867

Maier, T.; B�ck, A.

Generation of active [NiFe] hydrogenase in vitro from a nickel-free precursor form

Biochemistry

35

10089-10093

1996

Escherichia coli (P0AEV9)

8756471

brenda

692147

Rossmann, R.M.; Sauter, M.; Lottspeich, F.; B�ck, A.

Maturation of the large subunit (HYCE) of Escherichia coli hydrogenase 3 requires nickel incorporation followed by C-terminal processing at Arg537

Eur. J. Biochem.

220

377-384

1994

Escherichia coli (P0AEV9)

8125094

brenda

692148

Rossmann, R.; Maier, T.; Lottspeich, F.; Boeck, A.

Characterization of a protease from Escherichia coli involved in hydrogenase maturation

Eur. J. Biochem.

227

545-550

1995

Escherichia coli (P0AEV9)

7851435

brenda

711075

Kumarevel, T.; Tanaka, T.; Bessho, Y.; Shinkai, A.; Yokoyama, S.

Crystal structure of hydrogenase maturating endopeptidase HycI from Escherichia coli

Biochem. Biophys. Res. Commun.

389

310-314

2009

Escherichia coli K-12 (P0AEV9)

19720045

brenda

Entries 1 - 20 of 8

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