3.4.23.50: human endogenous retrovirus K endopeptidase
This is an abbreviated version!
For detailed information about human endogenous retrovirus K endopeptidase, go to the full flat file.
Reaction
Processing at the authentic HIV-1 PR recognition site and release of the mature p17 matrix and the p24 capsid protein, as a result of the cleavage of the -SQNY-/-PIVQ- cleavage site. =
Synonyms
endogenous retrovirus encoded protease, endogenous retrovirus HERV-K10 putative protease, HERV K10 endopeptidase, HERV K10 retropepsin, HERV-K PR, HERV-K protease, HERV-K(HML-2) Pro, HERV-K(HML-2) protease, HERV-K113 protease, HML-2 Pro, human endogenous retrovirus K retropepsin, human endogenous retrovirus K113 protease, human retrovirus K10 retropepsin, More
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KM Value
KM Value on EC 3.4.23.50 - human endogenous retrovirus K endopeptidase
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0.002
-
pH 5.0, 25°C, 13000 Da C-terminally truncated enzyme form
0.041
2-aminobenzoyl-Ala-Thr-His-Gln-Val-Tyr-Phe(NO2)-Val-Arg-Lys-Ala
-
pH 5.0, 25°C, 18000 Da enzyme form
0.001
-
pH 4.5, 11600 Da core domain
0.0103
Lys-Ala-Arg-Val-Tyr-Phe(NO2)-Glu-Ala-Nle-NH2
-
pH 4.5, 18200 Da enzyme form