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3.4.23.5: cathepsin D

This is an abbreviated version!
For detailed information about cathepsin D, go to the full flat file.

Word Map on EC 3.4.23.5

Reaction

Specificity similar to, but narrower than, that of pepsin A. Does not cleave the Gln4-His bond in B chain of insulin =

Synonyms

BmCatD, CAD 1, CAD 2, CAD 3, CapD, Cat D, CAT-D, CatD, Cath D, cath-D, cathD, cathepsin D, cathepsin D-like proteinase, cathepsin D1, cathepsin D2, CD1, CTSD, EC 3.4.4.23, matCTSD, PCD, Pep4p, preproCatD, pro-cathepsin, pro-cathepsin D, pro-CD, pro-CtsD, proCat, proCDrec, proCTSD, Proteinase A

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.5 cathepsin D

Crystallization

Crystallization on EC 3.4.23.5 - cathepsin D

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
cathepsin D complexed with the 6-peptide inhibitor pepstatin A
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cathepsin D and a complex with pepstatin at 2.5 A resolution
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cathepsin D complexed with the 6-peptide inhibitor pepstatin A
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in complex with inhibitors, hanging drop vapor diffusion method, using 35% (w/v) PEG2000, 0.1 M Na-acetat (pH 5.5)