3.4.23.47: HIV-2 retropepsin

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For detailed information about HIV-2 retropepsin, go to the full flat file.

Reaction

Endopeptidase for which the P1 residue is preferably hydrophobic =

Synonyms

HIV-2 protease, HIV-2 proteinase, human immunodeficiency virus 2 retropepsin, More, PR, PR2, retroviral aspartic proteinase, retroviral proteinase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.47 HIV-2 retropepsin

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Results	in table
2	Activating Compound
15	AA Sequence
13	Application
1	CAS Registry Number
14	Cloned(Commentary)
13	Crystallization (Commentary)
5	General Information
1	General Stability
51	IC50 Value
66	Inhibitors
6	kcat/KM [mM/s]
23	Ki Value [mM]
31	KM Value [mM]
1	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
30	Organism
2	Oxidation Stability
10	PDB ID
7	pH Optimum
1	Posttranslational Modification
28	Protein Variants
9	Purification (Commentary)
2	Reaction
1	Reaction Type
29	Reference
1	Renatured (Commentary)
3	Storage Stability
68	Substrates and Products (Substrate)
10	Subunits
25	Synonyms
4	Temperature Optimum [°C]
1	Temperature Stability [°C]
34	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 3.4.23.47 - HIV-2 retropepsin

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

1.1

IPFAAAQQRK

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370

2.3

KARLMAEALK

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370

0.2

VLQNYPIVQ

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370

3.3

VSQLYPIVQ

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370

10.8

VSQVYPIVQ

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370

0.8

VVQNYPIVQ

Human immunodeficiency virus 2

-

pH 5.6, 37°C

718370