3.4.23.46: memapsin 2
This is an abbreviated version!
For detailed information about memapsin 2, go to the full flat file.
Word Map on EC 3.4.23.46
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3.4.23.46
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alzheimer
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presenilins
-
plaque
-
abeta
-
notch
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amyloid-beta
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tau
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deficit
-
cerebral
-
neurodegenerative
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dementia
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hippocampus
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early-onset
-
amyloidogenic
-
neuropathological
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adam10
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beta-peptide
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intramembrane
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neurofibrillary
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synaptic
-
neuritic
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tangle
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neuroblastoma
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cortical
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nicastrin
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psen1
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neurotoxic
-
senile
-
neuroprotective
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csf
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sh-sy5y
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epsilon4
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hyperphosphorylation
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endoproteolysis
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anti-ad
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maze
-
ad-related
-
disintegrin
-
analysis
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ectodomain
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holoproteins
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anti-alzheimer
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beta-protein
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dapt
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insulin-degrading
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medicine
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swedish
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ad-like
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pharmacology
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abeta1-42
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neprilysin
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amyloidogenesis
-
angiopathy
- 3.4.23.46
- alzheimer
-
presenilins
- plaque
- abeta
- notch
- amyloid-beta
- tau
- deficit
- cerebral
- neurodegenerative
- dementia
- hippocampus
-
early-onset
-
amyloidogenic
-
neuropathological
- adam10
- beta-peptide
-
intramembrane
-
neurofibrillary
- synaptic
-
neuritic
- tangle
- neuroblastoma
- cortical
-
nicastrin
- psen1
-
neurotoxic
-
senile
-
neuroprotective
- csf
-
sh-sy5y
-
epsilon4
-
hyperphosphorylation
-
endoproteolysis
-
anti-ad
-
maze
-
ad-related
-
disintegrin
- analysis
- ectodomain
-
holoproteins
-
anti-alzheimer
- beta-protein
- dapt
-
insulin-degrading
- medicine
-
swedish
-
ad-like
- pharmacology
- abeta1-42
- neprilysin
-
amyloidogenesis
- angiopathy
Reaction
broad endopeptidase specificity. Cleaves Glu-Val-Asn-Leu-/-Asp-Ala-Glu-Phe in the Swedish variant of Alzheimer's amyloid precursor protein =
Synonyms
alpha-secretase, amyloid precursor protein secretase, APP secretase, Asec-1A, aspartic protease BACE, aspartic protease BACE1, Aspartic proteinase, aspartic proteinase BACE1, BACE, BACE 1, BACE I, BACE-1, BACE-2, BACE1, BACE1/beta-secretase, BACE2, beta protein amyloidogenase, beta secretase, beta-amyloid cleaving enzyme, beta-amyloid cleaving enzyme 1, beta-amyloid cleaving enzyme-1, beta-amyloid precursor protein cleavage enzyme 1, beta-amyloid precursor protein cleaving enzyme, beta-amyloid protein precursor secretase, beta-amyloid-cleaving enzyme, beta-amyloid-converting enzyme-1, beta-APP cleaving enzyme 1, beta-secretase, beta-secretase enzyme 1, beta-secretase-1, beta-site Alzheimer's amyloid precursor protein cleaving enzyme 1 (BACE1), beta-site amyloid cleaving enzyme, beta-site amyloid precursor protein cleavage enzyme, beta-site amyloid precursor protein cleaving enzyme, beta-site amyloid precursor protein cleaving enzyme 1, beta-site amyloid precursor protein cleaving enzyme-1, beta-site amyloid precursor protein enzyme 1, beta-site amyloid precursor protein-cleaving enzyme, beta-site amyloid precursor protein-cleaving enzyme 1, beta-site APP (amyloid precursor protein) cleaving enzyme, beta-site APP cleaving enzyme, beta-site APP cleaving enzyme 1, beta-site APP cleaving enzyme-1, beta-site APP-cleaving enzyme 1, D-aspartyl-beta-amyloid secretase, gamma-secretase, memapsin 1, memapsin 2, memapsin2, membrane-bound aspartic protease, NACE1, presenilin 1, presenilin-1, presenilin-2, protease Asp2, proteinase BACE1