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3.4.23.42: thermopsin

This is an abbreviated version!
For detailed information about thermopsin, go to the full flat file.

Word Map on EC 3.4.23.42

Reaction

similar in specificity to pepsin A preferring bulky hydrophobic amino acids in P1 and P1' =

Synonyms

EC 3.4.99.43, More, MTP-1, SsMTP, SSO1175, SSO2045, Sulfolobus solfataricus multidomain thermopsin-like protease, thpS

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.42 thermopsin

Substrates Products

Substrates Products on EC 3.4.23.42 - thermopsin

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Bovine insulin B-chain + H2O
?
show the reaction diagram
Bovine serum albumin + H2O
?
show the reaction diagram
-
-
-
-
?
carbonic anhydrase + H2O
?
show the reaction diagram
-
-
-
-
?
chicken egg albumin + H2O
?
show the reaction diagram
-
-
-
-
?
FVNQHLCGSHLVEALYLVCGERGFFYTPKA + H2O
FVNQHLCGSHL + VEAL + YLVCGERGF + L-Phe + YTPKA
show the reaction diagram
-
substrate insulin B chain
-
-
?
glyceraldehyde-3-phosphate dehydrogenase + H2O
?
show the reaction diagram
-
-
-
-
?
Hemoglobin + H2O
?
show the reaction diagram
insulin B chain + H2O
?
show the reaction diagram
Lys-Pro-Ala-Glu-Phe-(4-nitro)Phe-Ala-Leu + H2O
Lys-Pro-Ala-Glu-Phe + (4-nitro)Phe-Ala-Leu
show the reaction diagram
Lys-Pro-Ala-Glu-Phe-Nph-Ala-Leu + H2O
Lys-Pro-Ala-Glu-Phe + Nph-Ala-Leu
show the reaction diagram
-
synthetic chromogenic substrate
-
-
?
N-CBZ-glycine 4-nitrophenyl ester + H2O
N-CBZ-Gly + 4-nitrophenol
show the reaction diagram
ovalbumin + H2O
?
show the reaction diagram
-
-
-
-
?
oxidized insulin B + H2O
?
show the reaction diagram
-
following bonds are hydrolyzed: Leu-Val, Leu-Tyr, Phe-Phe, Phe-Tyr, Tyr-Thr
-
-
?
Protein + H2O
?
show the reaction diagram
-
in growth medium
-
-
?
additional information
?
-