3.4.23.31: Scytalidopepsin A

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For detailed information about Scytalidopepsin A, go to the full flat file.

Reaction

Hydrolysis of proteins with specificity similar to that of pepsin A, but also cleaves Cys(SO3H)7-/-Gly and Leu17-/-Val in the B chain of insulin =

Synonyms

Proteinase, Scytalidium lignicolum aspartic, Proteinase, Scytalidium lignicolum aspartic, A-2, Proteinase, Scytalidium lignicolum aspartic, A-I, Proteinase, Scytalidium lignicolum aspartic, C-, Scytalidium aspartic proteinase A, Scytalidium lignicolum acid proteinase, Scytalidium lignicolum aspartic proteinase, Scytalidium lignicolum carboxyl proteinase, Scytalidium sp. pepstatin-insensitive carboxyl proteinase A

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.31 Scytalidopepsin A

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Results	in table
1	CAS Registry Number
15	Inhibitors
15	KM Value [mM]
1	Localization
2	Metals/Ions
5	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
58	Organism
4	pH Optimum
1	pH Range
4	pH Stability
2	pI Value
10	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
1	Reaction Type
18	Reference
5	Source Tissue
2	Specific Activity [micromol/min/mg]
72	Substrates and Products (Substrate)
9	Synonyms
2	Temperature Optimum [°C]
1	Temperature Range [°C]
6	Temperature Stability [°C]

Temperature Stability

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Temperature Stability on EC 3.4.23.31 - Scytalidopepsin A

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TEMPERATURE STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

37

2 entries

50

Scytalidium lignicola

-

pH 4.0, 15 min, stable below

30754

55

Scytalidium lignicola

-

pH 4.8, 15 min, stable below

30756

60

Scytalidium lignicola

-

pH 4.0, 15 min, 60% loss of activity

30754

68

Scytalidium lignicola

-

pH 4.8, 15 min, complete loss of activity

30756

37

Scytalidium lignicola

-

pH 2.5-5.5, 20 h, stable

30754

37

Scytalidium lignicola

-

pH 3-5, 20 h, stable

30756