3.4.23.28: Acrocylindropepsin

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For detailed information about Acrocylindropepsin, go to the full flat file.

Reaction

Preference for hydrophobic residues at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves Leu6-/-Cys(SO3H), Glu21-/-Arg and Asn3-/-Gln, although not Gln4-His =

Synonyms

Acrocylindricum proteinase, Acrocylindrium acid proteinase, Acrocylindrium proteinase, EC 3.4.23.6, EC 3.4.4.17, EC 3.4.99.1, More, Proteinase, Acrocylindricum

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.28 Acrocylindropepsin

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Results	in table
7	AA Sequence
1	CAS Registry Number
2	Crystallization (Commentary)
6	Inhibitors
1	Localization
3	Natural Substrates/ Products (Substrates)
3	Organism
1	pH Optimum
1	pH Stability
1	Purification (Commentary)
1	Reaction
1	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
8	Substrates and Products (Substrate)
8	Synonyms
1	Temperature Optimum [°C]
2	Temperature Stability [°C]

Reaction Type

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Reaction Type on EC 3.4.23.28 - Acrocylindropepsin

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REACTION TYPE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

hydrolysis of peptide bond

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aspartic proteinase

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