3.4.23.28: Acrocylindropepsin

This is an abbreviated version, for detailed information about Acrocylindropepsin, go to the full flat file.

Reaction

Preference for hydrophobic residues at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves Leu6-/-Cys(SO3H), Glu21-/-Arg and Asn3-/-Gln, although not Gln4-His =

Synonyms

Acrocylindricum proteinase, Acrocylindrium acid proteinase, Acrocylindrium proteinase, EC 3.4.23.6, EC 3.4.99.1, More, Proteinase, Acrocylindricum

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.28 Acrocylindropepsin