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3.4.23.24: Candidapepsin

This is an abbreviated version!
For detailed information about Candidapepsin, go to the full flat file.

Word Map on EC 3.4.23.24

Reaction

Preferential cleavage at the carboxyl of hydrophobic amino acids, but fails to cleave Leu15-Tyr, Tyr16-Leu and Phe24-Phe of insulin B chain. Activates trypsinogen, and degrades keratin =

Synonyms

Aspartate protease, aspartic protease, aspartic protease 2, aspartic protease Sap2p, aspartic proteinase 3, aspartyl protease, aspartyl protease Sap2p, aspartyl protease Sap4, aspartyl protease Sap5, aspartyl protease Sap6, aspartyl proteinase, candialbicin, Candida albicans aspartic proteinase, Candida albicans carboxyl proteinase, Candida albicans secretory acid proteinase, Candida albicans-secreted aspartic proteinase, Candida olea acid proteinase, Candidapepsin-1, candidapepsin-2, EC 3.4.23.6, EC 3.4.4.17, Proteinase, Candida albicans aspartic, Proteinase, Candida aspartic, Proteinase, Candida olea aspartic, S-aspartyl proteinase, SAP, SAP1, Sap10, SAP11, Sap1p, SAP2, Sap2p, SAP2X, SAP3, Sap3p, SAP4, Sap4p, SAP5, Sap5p, SAP6, Sap6p, Sap7, Sap7p, Sap8, Sap8p, Sap9, Sap9p, SAPP1, Sapp1p, SAPP2, Sapp2p, SAPP3, SAPT1, Sapt1p, SAPT2, SAPT3, SAPT4, secreted aspartic protease, secreted aspartic protease 1, secreted aspartic protease 2, secreted aspartic proteinase, secreted aspartic proteinase 1, secreted aspartic proteinase 2, secreted aspartic proteinase-2, secreted aspartyl peptidase, secreted aspartyl protease, secreted aspartyl protease 9, secreted aspartyl proteinase, secreted aspartyl proteinase 2, secreted aspartyl proteinase 5, secreted aspartyl proteinase2, secreted aspartyl proteinases, secreted aspartyl-type peptidase, secretory aspartyl proteinase, secretory aspartyl proteinase SAP1, secretory aspartyl proteinase SAP2p, secretory aspartyl proteinase SAP3p, secretory aspartyl proteinase SAP4p, secretory aspartyl proteinase SAP5p, secretory aspartyl proteinase SAP6p, yapsin, Yps

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.24 Candidapepsin

Natural Substrates Products

Natural Substrates Products on EC 3.4.23.24 - Candidapepsin

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Bovine serum albumin + H2O
?
show the reaction diagram
-
-
-
-
?
casein + H2O
?
show the reaction diagram
complement component 3b + H2O
?
show the reaction diagram
substrate for isoforms Sapp1p and Sapp2p
-
-
?
complement component 4b + H2O
?
show the reaction diagram
substrate for isoforms Sapp1p and Sapp2p
-
-
?
complement component C3b + H2O
?
show the reaction diagram
-
-
-
-
?
complement component C4b + H2O
?
show the reaction diagram
-
-
-
-
?
complement component C5 + H2O
?
show the reaction diagram
-
-
-
-
?
factor H + H2O
?
show the reaction diagram
factor H-related protein 5 + H2O
?
show the reaction diagram
substrate for isoform Sapp2p
-
-
?
macrophage factor H-receptor CR3 + H2O
?
show the reaction diagram
-
the enzyme cleaves and inactivates macrophage factor H-receptor CR3
-
-
?
macrophage factor H-receptor CR4 + H2O
?
show the reaction diagram
-
the enzyme cleaves and inactivates macrophage factor H-receptor CR4
-
-
?
protein + H2O
hydrolyzed protein
show the reaction diagram
additional information
?
-