3.4.23.22: Endothiapepsin

This is an abbreviated version!
For detailed information about Endothiapepsin, go to the full flat file.

Reaction

hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk =

Synonyms

Aspartate protease, Aspartic proteinase, EC 3.4.23.10, EC 3.4.23.6, EC 3.4.4.17, Endothia acid proteinase, Endothia aspartic proteinase, Endothia parasitica acid proteinase, Endothia parasitica aspartic proteinase, Proteinase, Endothia aspartic

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.22 Endothiapepsin

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
2	AA Sequence
3	Application
1	CAS Registry Number
1	Cloned(Commentary)
18	Crystallization (Commentary)
1	General Stability
23	IC50 Value
66	Inhibitors
12	Ki Value [mM]
2	KM Value [mM]
6	Molecular Weight [Da]
29	Organism
780	PDB ID
3	pH Optimum
2	pH Stability
1	pI Value
1	Posttranslational Modification
4	Purification (Commentary)
3	Reaction
1	Reaction Type
29	Reference
2	Specific Activity [micromol/min/mg]
11	Substrates and Products (Substrate)
4	Subunits
10	Synonyms
1	Temperature Optimum [°C]

Reaction

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Reaction on EC 3.4.23.22 - Endothiapepsin

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to Reaction Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

REACTION

REACTION DIAGRAM

COMMENTARY

ORGANISM

UNIPROT

LITERATURE

hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk

3 entries

hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk

-

-

-

-

hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk

the enzyme contains a catalytic Asp dyad

Cryphonectria parasitica

-

670005

hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk

catalytic mechanism, X-ray, neutron and NMR studies

Cryphonectria parasitica

-

679599