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3.4.23.21: Rhizopuspepsin

This is an abbreviated version!
For detailed information about Rhizopuspepsin, go to the full flat file.

Word Map on EC 3.4.23.21

Reaction

hydrolysis of proteins with broad specificity similar to that of pepsin A, preferring hydrophobic residues at P1 and P1'. Clots milk and activates trypsinogen. Does not cleave Gln4-His, but does cleave His10-/-Leu and Val12-/-Glu in B chain of insulin =

Synonyms

Aspartate protease, aspartic peptidase, EC 3.4.23.6, EC 3.4.23.9, EC 3.4.4.17, EC 3.4.99.25, More, Neurase, Proteinase, Rhizopus acid, Rhizopus acid protease, Rhizopus acid proteinase, Rhizopus aspartic proteinase, rhizopuspepsinogen

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.21 Rhizopuspepsin

KM Value

KM Value on EC 3.4.23.21 - Rhizopuspepsin

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.036
Abz-LSFMAIQ-EDDnp
-
at pH 5.5 and 50°C
0.23 - 1.1
Ac-Ala-Ala-Lys-(4-nitro)Phe-Ala-Ala
0.006 - 0.269
KAIEF p-nitrophenylalanine-RL
0.007 - 0.139
KLIEF p-nitrophenylalanine-RL
0.008 - 0.089
KPAEF p-nitrophenylalanine-RL
0.004 - 0.013
KPALF p-nitrophenylalanine-RL
0.01 - 0.065
KPDEF p-nitrophenylalanine-RL
0.006 - 0.157
KPIAF p-nitrophenylalanine-RL
0.003 - 0.211
KPIDF p-nitrophenylalanine-RL
0.002 - 0.057
KPIEF p-nitrophenylalanine-RL
0.006 - 0.056
KPILF p-nitrophenylalanine-RL
0.003 - 0.047
KPISF p-nitrophenylalanine-RL
0.004 - 0.101
KPLEF p-nitrophenylalanine-RL
0.008
KPREF p-nitrophenylalanine-RL
-
pH 3.0, 37°C
0.007 - 0.108
KPSEF p-nitrophenylalanine-RL
0.0034
KPVSY(4-NO2-F)RL
-
-
0.0034
KPVSY(NO2)FRL
-
pH 7.4, 37°C
0.009 - 0.21
KSIEF p-nitrophenylalanine-RL