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3.4.23.2: pepsin B

This is an abbreviated version!
For detailed information about pepsin B, go to the full flat file.

Word Map on EC 3.4.23.2

Reaction

degradation of gelatin; little activity on hemoglobin. Specificity on B chain of insulin additional information restricted than that of pepsin A; does not cleave at Phe1-Val, Gln4-His or Gly23-Phe =

Synonyms

EC 3.4.4.2, gelatinase, More, parapepsin I, pepsin, Pepsina Suina TS

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.23 Aspartic endopeptidases
                3.4.23.2 pepsin B

pH Range

pH Range on EC 3.4.23.2 - pepsin B

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pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
1 - 5.5
-
hemoglobin, pH 1: about 50% of maximum activity, pH 5.5: about 10% of maximum activity
2 - 3.4
-
-
2.5 - 5
-
pH 2.5: about 20% of maximal activity, pH 3.0: about 70% of maximal activity, pH 4.0: about 50% of maximal activity
additional information
-
milk clotting activity below pH 6.6