3.4.22.B76: Allium alpha-fibrinogenase AFTEII

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For detailed information about Allium alpha-fibrinogenase AFTEII, go to the full flat file.

Reaction

the enzyme degrades the Aalpha-chain of human fibrinogen but not the Bbeta-chain =

Synonyms

AFTEII, alpha-Fibrinogenase

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B76 Allium alpha-fibrinogenase AFTEII

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Results	in table
1	Application
2	Inhibitors
1	Molecular Weight [Da]
1	Organism
1	pH Optimum
1	pI Value
1	Reaction
1	Reference
2	Substrates and Products (Substrate)
1	Subunits
2	Synonyms
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 3.4.22.B76 - Allium alpha-fibrinogenase AFTEII

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

Human fibrinogen + H2O

?

Allium tuberosum

-

cleavage of the Aalpha-chain, but not of the Bbeta-chain or the gamma-chain by AFTEII

722928

-

-

?

MeO-Suc-Arg-Pro-Tyr-4-nitroanilide + H2O

?

Allium tuberosum

-

i.e. S-2586, ATFEII is highly specific for the chromogenic chymotrypsin substrate

722928

-

-

?