3.4.22.B75: SENP7 peptidase
This is an abbreviated version!
For detailed information about SENP7 peptidase, go to the full flat file.
Word Map on EC 3.4.22.B75
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3.4.22.B75
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senp7s
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hp1
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heterochromatin
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medicine
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deconjugation
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h3k9me3
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pericentric
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desumoylation
- 3.4.22.B75
- senp7s
- hp1
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heterochromatin
- medicine
-
deconjugation
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h3k9me3
-
pericentric
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desumoylation
Reaction
Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms. SENP67 prefers the LRGG-/- sequence versus the QTGG-/- sequence. =
Synonyms
SENP7, SENP7 SUMO-protease, sentrin-specific protease 7, sentrin/small ubiquitin-like modifier-specific protease 7, SUMO protease SENP7, SUMO-specific protease 7, SUMO-specific protease SENP7, SUMO/sentrin/Smt3-specific peptidase
ECTree
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Localization
Localization on EC 3.4.22.B75 - SENP7 peptidase
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enzyme SENP7 localization at pericentric domains depends on HP1 interaction motifs, the module of two PxVxL interaction motifs on SENP7 maintains HP1 enrichment at pericentric domains, localization study, overview