3.4.22.B72: SENP3 peptidase

This is an abbreviated version, for detailed information about SENP3 peptidase, go to the full flat file.

Reaction

The enzyme catalyzes the desumoylation of SUMO2 or SUMO3-modified target proteins, but has only weak activity against SUMO1 conjugates. SENP2 catalyzes deconjugation of SUMO2 from nucleophosmin 1. =

Synonyms

SENP3, sentrin-specific protease 3, small ubiquitin-like modifier-specific protease 3, SUMO-2/3-specific protease, SUMO-specific isopeptidase, SUMO-specific protease 3, SUMO-specific proteases 3, SUMO2/3-specific protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B72 SENP3 peptidase