3.4.22.B69: falcipain-2

This is an abbreviated version, for detailed information about falcipain-2, go to the full flat file.

Reaction

The enzyme plays a key role in the hydrolysis of hemoglobin by the parasite Plasmodium falciparum. Preferred cleavage sites display arginine in P1, leucine in P2, and phenylalanine in P1' =

Synonyms

falcipain 2, falcipain-2, FP-2, Fp2, haemoglobinase

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B69 falcipain-2