3.4.22.B68: EhCP4 proteinase

This is an abbreviated version, for detailed information about EhCP4 proteinase, go to the full flat file.

Reaction

unique preference for valine and isoleucine at P2 and broader specificities at the P1 and P3 positions, while proline at P4 is relatively selective =

Synonyms

CP4, cysteine proteinase 4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B68 EhCP4 proteinase

pH Stability

pH Stability on EC 3.4.22.B68 - EhCP4 proteinase

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pH STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
3 - 4
recombinant CP4 is efficiently autoactivated at pH 3.0-4.0 with 5 mM dithiothreitol, mature recombinant CP4 is unstable at acid pH and undergoes further degradation
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