3.4.22.B68: EhCP4 proteinase
This is an abbreviated version!
For detailed information about EhCP4 proteinase, go to the full flat file.
Reaction
unique preference for valine and isoleucine at P2 and broader specificities at the P1 and P3 positions, while proline at P4 is relatively selective =
Synonyms
CP4, cysteine proteinase 4
ECTree
3.4.22.B68 EhCP4 proteinaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 3.4.22.B68 - EhCP4 proteinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
benzyloxycarbonyl-VVR-7-amido-4-methylcoumarin + H2O
benzyloxycarbonyl-VVR + 7-amino-4-methylcoumarin
-
-
-
?
complement component C3 + H2O
?
-
the primary product is a fragment of 70000 Da, a size similar to that of complement component C3b which is further proteolytically degraded by CP4
-
?
complement component C3 + H2O
?
-
the primary product is a fragment of 70000 Da, a size similar to that of complement component C3b which is further proteolytically degraded by CP4
-
?
Protein + H2O
?
CP4 displays a unique preference for valine and isoleucine at P2 (Val > Ile) and broader specificities at the P1 and P3 positions, while at P4 proline is relatively selective
-
-
?
Protein + H2O
?
CP4 displays a unique preference for valine and isoleucine at P2 (Val > Ile) and broader specificities at the P1 and P3 positions, while at P4 proline is relatively selective
-
-
?
succinyl-LLVY-7-amido-4-methylcoumarin + H2O
succinyl-LLVY + 7-amino-4-methylcoumarin
-
-
-
?
succinyl-LLVY-7-amido-4-methylcoumarin + H2O
succinyl-LLVY + 7-amino-4-methylcoumarin
-
-
-
?
additional information
?
-
recombinant CP4 does not cleave benzyloxycarbonyl-RR-7-amido-4-methylcoumarin or benzyloxycarbonyl-FR-7-amido-4-methylcoumarin
-
-
?
additional information
?
-
recombinant CP4 does not cleave benzyloxycarbonyl-RR-7-amido-4-methylcoumarin or benzyloxycarbonyl-FR-7-amido-4-methylcoumarin
-
-
?
