3.4.22.B68: EhCP4 proteinase

This is an abbreviated version, for detailed information about EhCP4 proteinase, go to the full flat file.

Reaction

unique preference for valine and isoleucine at P2 and broader specificities at the P1 and P3 positions, while proline at P4 is relatively selective =

Synonyms

CP4, cysteine proteinase 4

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B68 EhCP4 proteinase

Reference

Reference on EC 3.4.22.B68 - EhCP4 proteinase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
He, C.; Nora, G.P.; Schneider, E.L.; Kerr, I.D.; Hansell, E.; Hirata, K.; Gonzalez, D.; Sajid, M.; Boyd, S.E.; Hruz, P.; Cobo, E.R.; Le, C.; Liu, W.T.; Eckmann, L.; Dorrestein, P.C.; Houpt, E.R.; Brinen, L.S.; Craik, C.S.; Roush, W.R.; McKerrow, J.; Reed, S.L.
A novel Entamoeba histolytica cysteine proteinase, EhCP4, is key for invasive amebiasis and a therapeutic target
J. Biol. Chem.
285
18516-18527
2010
Entamoeba histolytica (C4LTT0), Entamoeba histolytica HM1-IMSS (C4LTT0)
Manually annotated by BRENDA team
Vatanshenassan, M.; Rezaie, S.; Mohebali, M.; Niromand, N.; Kazemi, B.; Babaei, Z.; Rezaeian, M.
Trichomonas vaginalis: investigation of a novel diagnostic method in urine samples using cysteine proteinase 4 gene and PCR technique
Exp. Parasitol.
126
187-190
2010
Trichomonas vaginalis
Manually annotated by BRENDA team