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3.4.22.B65: cathepsin P

This is an abbreviated version!
For detailed information about cathepsin P, go to the full flat file.

Word Map on EC 3.4.22.B65

Reaction

Hydrolysis of proteins with restricted preference for substrates containing hydrophobic amino acids. Efficiently cleaves -Glu-Ile-Phe-/-Val-Phe-Lys-Gln-. Involved in the processing of endoplasmic proteins =

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B65 cathepsin P

KI Value

KI Value on EC 3.4.22.B65 - cathepsin P

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.000032
CBZ-Trp-Trp-4-cyclohexanone-Trp-Phe-OMe
pH 6.5, 37°C
0.002
E-64
37°C, presence of 1.5 M NaSO4