3.4.22.B65: cathepsin P

This is an abbreviated version!
For detailed information about cathepsin P, go to the full flat file.

Word Map on EC 3.4.22.B65

3.4.22.B65

cathepsins

papain

peptidyl

rodent

lysosomal

proenzyme

tubule

phe

perimembranous

kupffer

cytred

giant

papain-like

peptidases

propeptide

pecs

rcho-1

hepatocytes

na2so4

immunolocalization

trophoblast

choriocarcinoma

preproprotein

Reaction

Hydrolysis of proteins with restricted preference for substrates containing hydrophobic amino acids. Efficiently cleaves -Glu-Ile-Phe-/-Val-Phe-Lys-Gln-. Involved in the processing of endoplasmic proteins =

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.B65 cathepsin P

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Results	in table
10	Activating Compound
1	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
4	Inhibitors
2	Ki Value [mM]
43	KM Value [mM]
2	Localization
5	Molecular Weight [Da]
1	Organic Solvent Stability
6	Organism
2	pH Optimum
1	pH Range
2	Posttranslational Modification
1	Purification (Commentary)
1	Reaction
6	Reference
5	Source Tissue
49	Substrates and Products (Substrate)
1	Subunits
1	Temperature Optimum [°C]
43	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 3.4.22.B65 - cathepsin P

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dithiothreitol

activation

hyaluronate

Na2SO4

NaBr