3.4.22.B63: sortase C

This is an abbreviated version!
For detailed information about sortase C, go to the full flat file.

Reaction

The enzyme from Bacillus anthracis cleaves the LPNT-/-A sorting signal of BasH and BasI, thereby anchoring both polypeptides to the cell wall envelope of sporulating bacilli [17074072]. The enzymes from Streptococcus pneumoniae and Enterococcus faecalis are required for efficient pilus assembly. =

Synonyms

pilus-associated sortase C, sortase C, sortase C1, sortase C2, sortaseC1, Srt-2, SrtC, SrtC-1, SrtC-2, SrtC-3, SrtC1, SrtC2, SrtC_1, SrtC_2, yhhA

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B63 sortase C

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Results	in table
5	AA Sequence
8	Cloned(Commentary)
9	Crystallization (Commentary)
4	General Information
2	Inhibitors
12	kcat/KM [mM/s]
14	KM Value [mM]
2	Localization
1	Metals/Ions
2	Molecular Weight [Da]
16	Natural Substrates/ Products (Substrates)
28	Organism
8	Protein Variants
7	Purification (Commentary)
1	Reaction
23	Reference
1	Source Tissue
20	Substrates and Products (Substrate)
5	Subunits
40	Synonyms
12	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 3.4.22.B63 - sortase C

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kcat/KM VALUE [1/mMs^-1]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

16.2 - 810

Dabcyl-ancillary protein 1-Edans

4 entries

-

159 - 797

Dabcyl-ancillary protein 2-Edans

4 entries

-

243 - 922

Dabcyl-BP-1 peptide-Edans

4 entries

-

16.2

Dabcyl-ancillary protein 1-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC2, at pH 7.5 and 37°C

732709

-

32.5

Dabcyl-ancillary protein 1-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC1, at pH 7.5 and 37°C

732709

-

38.1

Dabcyl-ancillary protein 1-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

Y92A mutant isoform SrtC1, at pH 7.5 and 37°C

732709

-

810

Dabcyl-ancillary protein 1-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

F86A mutant isoform SrtC2, at pH 7.5 and 37°C

732709

-

159

Dabcyl-ancillary protein 2-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC2, at pH 7.5 and 37°C

732709

-

226

Dabcyl-ancillary protein 2-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

F86A mutant isoform SrtC2, at pH 7.5 and 37°C

732709

-

470

Dabcyl-ancillary protein 2-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC1, at pH 7.5 and 37°C

732709

-

797

Dabcyl-ancillary protein 2-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

Y92A mutant isoform SrtC1, at pH 7.5 and 37°C

732709

-

243

Dabcyl-BP-1 peptide-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

F86A mutant isoform SrtC2, at pH 7.5 and 37°C

732709

-

339

Dabcyl-BP-1 peptide-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC2, at pH 7.5 and 37°C

732709

-

570

Dabcyl-BP-1 peptide-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

wild type isoform SrtC1, at pH 7.5 and 37°C

732709

-

922

Dabcyl-BP-1 peptide-Edans

Streptococcus agalactiae serogroup V

Q8E0S7

Y92A mutant isoform SrtC1, at pH 7.5 and 37°C

732709

-