3.4.22.B61: cathepsin L5
This is an abbreviated version!
For detailed information about cathepsin L5, go to the full flat file.
Word Map on EC 3.4.22.B61
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3.4.22.B61
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fasciola
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cathepsins
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hepatica
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fluke
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subsite
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medicine
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evasion
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l-like
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gigantica
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helminth
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cattle
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sheep
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metacercariae
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stage-specific
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excysted
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multivalent
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veterinary
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agriculture
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diagnostics
- 3.4.22.B61
- fasciola
- cathepsins
- hepatica
- fluke
-
subsite
- medicine
-
evasion
-
l-like
- gigantica
-
helminth
- cattle
- sheep
-
metacercariae
-
stage-specific
-
excysted
-
multivalent
-
veterinary
- agriculture
- diagnostics
Reaction
cathepsin L5 does not exhibit substantial catalytic activity against substrates containing proline in the P2 position (thereby distinguished from Fasciola cathepsin L1, L2 and L3) =
Synonyms
Cat L5, cathepsin L5, CatL5, FhCatL5, FhCL5, FhpCL5
ECTree
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Turnover Number
Turnover Number on EC 3.4.22.B61 - cathepsin L5
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11.05
mutant enzyme L69W, at pH 5.5 and 37°C
17.89
benzyloxycarbonyl-L-Phe-L-Arg-7-amido-4-methylcoumarin
wild type enzyme, at pH 5.5 and 37°C
2145
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin
FhCatL5-L69Y
0.84
wild type enzyme, at pH 5.5 and 37°C
1.34
tosyl-Gly-L-Pro-L-Arg-7-amido-4-methylcoumarin
mutant enzyme L69W, at pH 5.5 and 37°C
0.19
mutant enzyme L69C, at pH 5.5 and 37°C
0.27
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin
mutant enzyme L69S, at pH 5.5 and 37°C
0.84
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin
wild type enzyme, at pH 5.5 and 37°C
1.78
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin
mutant enzyme L69Y, at pH 5.5 and 37°C
2.54
tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin
mutant enzyme L69Y, at pH 5.5 and 37°C
1.73
mutant enzyme L69S, at pH 5.5 and 37°C
1.92
Z-Phe-Arg-7-amido-4-methylcoumarin
mutant enzyme L69C, at pH 5.5 and 37°C
17.89
Z-Phe-Arg-7-amido-4-methylcoumarin
wild type enzyme, at pH 5.5 and 37°C
17.93
Z-Phe-Arg-7-amido-4-methylcoumarin
mutant enzyme L69F, at pH 5.5 and 37°C
21.52
Z-Phe-Arg-7-amido-4-methylcoumarin
mutant enzyme L69Y, at pH 5.5 and 37°C