3.4.22.B60: cathepsin L2

This is an abbreviated version, for detailed information about cathepsin L2, go to the full flat file.

Reaction

preference for Arg in the P1 position, Pro is accepted in the P2 position =

Synonyms

cathepsin L2, cathepsin L2 protease, CatL2, CL2, FhCatL2, FhCL2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B60 cathepsin L2

Inhibitors

Inhibitors on EC 3.4.22.B60 - cathepsin L2

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
benzyloxycarbonyl-Phe-Ala-diazomethyl ketone
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FheCL2
cathepsin K inhibitor II
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Tetranitromethane
cathepsin L2 is completely inactivated by 4 mM tetranitromethane, cathepsin L1 is not inactivated
Z-Phe-Ala-CHN2
-
-
additional information
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fibrin clot formation by cathepsin L is not inhibited by the thrombin inhibitor hirudin or by the anti-polymerant H-Gly-Pro-Arg-Pro-OH
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