3.4.22.B5: CPB protease

This is an abbreviated version, for detailed information about CPB protease, go to the full flat file.

Reaction

good cleavage of the Arg-Phe bond. The best substrate ortho-aminobenzoyl-KLR-/-FSKQ-(N-(2,4-dinitrophenyl)-ethylenediamine) is also well hydrolyzed by cathepsin L, however the best inhibitor of the parasite enzyme ortho-aminobenzoyl-KLRFSKQ-(N-(2,4-dinitrophenyl)-ethylenediamine) has low affinity to cathepsin L =

Synonyms

C01.074, CPB, cpb-like, CPB1, CPB10, CPB11, CPB12, CPB13, CPB14, CPB15, CPB16, CPB17, CPB18, CPB19, CPB2, CPB2.3, CPB2.8, CPB3, CPB4, CPB5, CPB6, CPB7, CPB8, CPB9, cystein protease CPB2.8, cysteine peptidase, cysteine peptidase B, cysteine protease B, cysteine protease CPB, cysteine proteinase B, cysteine proteinase type I, cysteine-proteinase B, LdcCys1, type I cysteine protease

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B5 CPB protease