3.4.22.B49: cathepsin L1

This is an abbreviated version!
For detailed information about cathepsin L1, go to the full flat file.

Word Map on EC 3.4.22.B49

3.4.22.B49

cathepsins

fasciola

hepatica

fluke

fasciolosis

metacercariae

helminth

gigantica

medicine

excysted

trematode

excretory-secretory

immunodiagnosis

agriculture

mimotopes

diagnostics

Reaction

clear preference for Arg at P1 position (Lys, Glu, Thr, and Met are less efficient). FheCL1 shows distinct preference for hydrophobic amino acids in the P2, Leu is favored. Cathepsin L1 can accommodate Pro in the P2 position, but less efficiently than cathepsin L2. FheCL1 produces clear degradation fragments from collagen =

Synonyms

cat-L1H, cathepsin L1, cathepsin L1 cysteine protease, cathepsin L1 protease, cathepsin L1 proteinase, cathepsin L1g, cathepsin L1H, CatL1, CgCTSL1, CGI_10027418, CL1, CPFhW, CTSL1, cysteine proteinase 3, Da-CTSL1, FgCatL1H, FhCL1, FheCL1, FhpCL1

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.22 Cysteine endopeptidases

3.4.22.B49 cathepsin L1

Advanced search results

Do not include text mining results

Include

results (more...)

Include

results (more...)

Results	in table
7	Activating Compound
14	AA Sequence
18	Application
1	CAS Registry Number
22	Cloned(Commentary)
1	Crystallization (Commentary)
83	Disease/ Diagnostics
3	Expression
8	General Information
39	IC50 Value
66	Inhibitors
6	Ki Value [mM]
44	KM Value [mM]
6	Localization
16	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
42	Organism
6	pH Optimum
4	pH Range
5	pH Stability
2	pI Value
7	Posttranslational Modification
10	Protein Variants
21	Purification (Commentary)
1	Reaction
1	Reaction Type
40	Reference
2	Renatured (Commentary)
29	Source Tissue
2	Specific Activity [micromol/min/mg]
74	Substrates and Products (Substrate)
14	Subunits
54	Synonyms
3	Temperature Optimum [°C]
1	Temperature Stability [°C]
43	Turnover Number [1/s]

KI Value

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

KI Value on EC 3.4.22.B49 - cathepsin L1

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide

Go to Ki Value Search

0.0000154 - 0.001125

benzyloxycarbonyl-Phe-Ala-diazomethyl ketone

3 entries

0.0000108 - 0.000116

cathepsin K inhibitor II

3 entries