3.4.22.B28: calpain 8
This is an abbreviated version!
For detailed information about calpain 8, go to the full flat file.
Word Map on EC 3.4.22.B28
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3.4.22.B28
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calpastatin
-
calcium-dependent
-
caspase
-
ca2+-dependent
-
cytoskeletal
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calpeptin
-
neurodegenerative
-
ischemia
-
neuroprotective
-
proteasome
-
calcium-activated
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alzheimer
-
synaptic
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cathepsins
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hippocampal
-
degeneration
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cortical
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proteinase
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platelet
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nmda
-
neurotoxicity
-
spectrin
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excitotoxicity
-
reperfusion
-
tau
-
meat
-
leupeptin
-
tender
-
traumatic
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ca2+-activated
-
ionophore
-
autolysis
-
myofibrillar
-
talin
-
n-methyl-d-aspartate
-
caspase-12
-
neurofilament
-
myofibril
-
proteolyzed
-
overactivation
-
longissimus
-
aif
-
desmin
-
lactacystin
-
caspase-independent
-
sarcomere
-
limb-girdle
-
bapta-am
-
nmda-induced
-
medicine
-
troponin-t
- 3.4.22.B28
- calpastatin
-
calcium-dependent
-
caspase
-
ca2+-dependent
- cytoskeletal
- calpeptin
- neurodegenerative
- ischemia
-
neuroprotective
- proteasome
-
calcium-activated
- alzheimer
- synaptic
- cathepsins
- hippocampal
- degeneration
- cortical
- proteinase
- platelet
- nmda
-
neurotoxicity
- spectrin
-
excitotoxicity
-
reperfusion
- tau
-
meat
- leupeptin
-
tender
-
traumatic
-
ca2+-activated
-
ionophore
-
autolysis
- myofibrillar
- talin
- n-methyl-d-aspartate
- caspase-12
- neurofilament
- myofibril
-
proteolyzed
-
overactivation
- longissimus
- aif
- desmin
- lactacystin
-
caspase-independent
- sarcomere
-
limb-girdle
- bapta-am
-
nmda-induced
- medicine
-
troponin-t
Reaction
broad endopeptidase specificity =
Synonyms
calpain, calpain 8/nCL-2, calpain-8a, CAPN 8, Capn8, CAPN9, More, nCL-2, nCL-2', nCL-2/calpain 8, stomach specific calpain nCL-2, stomach-specific calpain
ECTree
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Reference
Reference on EC 3.4.22.B28 - calpain 8
Please use the Reference Search for a specific query.
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Hata, S.; Nishi, K.; Kawamoto, T.; lee, H.; Kawahara, H.; Maeda, T.; Shintani, Y.; Sorimachi, H.; Suzuki, K.
Both the conserved and unique gene structure of stomach-specific calpains reveal processes of calpain gene evolution
J. Mol. Evol.
53
191-203
2001
Mus musculus, Mus musculus (Q91VA3)
Braun, C.; Engel, M.; Theisinger, B.; Welter, C.; Seifert, M.
CAPN 8: isolation of a new mouse calpain-isoenzyme
Biochem. Biophys. Res. Commun.
260
671-675
1999
Mus musculus
Hata, S.; Koyama, S.; Kawahara, H.; Doi, N.; Maeda, T.; Toyama-Sorimachi, N.; Abe, K.; Suzuki, K.; Sorimachi, H.
Stomach-specific calpain, nCL-2, localizes in mucus cells and proteolyzes the beta-subunit of coatomer complex, beta-COP
J. Biol. Chem.
281
11214-11224
2006
Mus musculus, Rattus norvegicus
Hata, S.; Doi, N.; Kitamura, F.; Sorimachi, H.
Stomach-specific calpain, nCL-2/calpain 8, is active without calpain regulatory subunit and oligomerizes through C2-like domains
J. Biol. Chem.
282
27847-27856
2007
Mus musculus
Raveendran, N.N.; Silver, K.; Freeman, L.C.; Narvaez, D.; Weng, K.; Ganta, S.; Lillich, J.D.
Drug-induced alterations to gene and protein expression in intestinal epithelial cell 6 cells suggest a role for calpains in the gastrointestinal toxicity of nonsteroidal anti-inflammatory agents
J. Pharmacol. Exp. Ther.
325
389-399
2008
Rattus norvegicus
Hata, S.; Abe, M.; Suzuki, H.; Kitamura, F.; Toyama-Sorimachi, N.; Abe, K.; Sakimura, K.; Sorimachi, H.
Calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, involved in gastric mucosal defense
PLoS Genet.
6
e1001040
2010
Mus musculus (Q91VA3)
Peng, P.; Wu, W.; Zhao, J.; Song, S.; Wang, X.; Jia, D.; Shao, M.; Zhang, M.; Li, L.; Wang, L.; Duan, F.; Zhao, R.; Yang, C.; Wu, H.; Zhang, J.; Shen, Z.; Ruan, Y.; Gu, J.
Decreased expression of Calpain-9 predicts unfavorable prognosis in patients with gastric cancer
Sci. Rep.
6
29604
2016
Homo sapiens (A6NHC0), Homo sapiens (O14815)
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