3.4.22.B24: calpain 4
This is an abbreviated version!
For detailed information about calpain 4, go to the full flat file.
Word Map on EC 3.4.22.B24
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3.4.22.B24
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calpains
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muscular
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dystrophy
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limb-girdle
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girdle
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lgmd2a
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mu-calpains
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capns1
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calpastatin
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calpain-mediated
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autolyzed
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medicine
- 3.4.22.B24
-
calpains
- muscular
-
dystrophy
-
limb-girdle
-
girdle
-
lgmd2a
- mu-calpains
- capns1
-
calpastatin
-
calpain-mediated
-
autolyzed
- medicine
Reaction
broad endopeptidase specificity =
Synonyms
calcium-activated neutral proteinase, calpain 4, calpain regulatory subunit, calpain small subunit, calpain small subunit 1, CANP, Capn4, Css-1, More
ECTree
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Inhibitors
Inhibitors on EC 3.4.22.B24 - calpain 4
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calpain inhibitor IV
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0.1 mg/ml, irreversible, attacks the active site of m-calpain nucleophilically, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired
calpeptin
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0.075 mg/ml, reversible, reacts with the active site of both my-calpain and m-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired
PD 151746
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0.1 mg/ml, reversible, binds predominantly to the Ca2+-binding site of my-calpain, the association between calpain 4 and alpha-p21-activated kinase interacting exchange factor (alpha-PIX) is not impaired