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3.4.22.B19: YopJ protease

This is an abbreviated version!
For detailed information about YopJ protease, go to the full flat file.

Word Map on EC 3.4.22.B19

Reaction

cleaves reversible post-translational modification in form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NfkappaB pathways in the infected cell =

Synonyms

C55.001, outer protein T, virulence factor YopJ, Yersinia outer protein, Yersinia outer protein J, Yersinia outer protein P, Yersinia outer protein T, YopJ, YopJKIM, YopP, YopT

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B19 YopJ protease

Substrates Products

Substrates Products on EC 3.4.22.B19 - YopJ protease

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Cdc42 + H2O
?
show the reaction diagram
-
-
-
-
?
IkappaBalpha-ubiquitin + H2O
IkappaBalpha + ubiquitin
show the reaction diagram
-
-
-
-
?
Rac1 + H2O
?
show the reaction diagram
-
-
-
-
?
RhoA + H2O
?
show the reaction diagram
-
-
-
-
?
TRAF2-ubiquitin + H2O
TRAF2 + ubiquitin
show the reaction diagram
TRAF3-ubiquitin + H2O
TRAF3 + ubiquitin
show the reaction diagram
TRAF6-ubiquitin + H2O
TRAF6 + ubiquitin
show the reaction diagram
ubiquitin-7-amido-4-methylcoumarin + H2O
ubiquitin + 7-amino-4-methylcoumarin
show the reaction diagram
-
-
-
-
?
additional information
?
-