3.4.22.B19: YopJ protease

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For detailed information about YopJ protease, go to the full flat file.

Reaction

cleaves reversible post-translational modification in form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NfkappaB pathways in the infected cell =

Synonyms

C55.001, outer protein T, virulence factor YopJ, Yersinia outer protein, Yersinia outer protein J, Yersinia outer protein P, Yersinia outer protein T, YopJ, YopJKIM, YopP, YopT

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B19 YopJ protease

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Results	in table
1	CAS Registry Number
2	Cloned(Commentary)
18	General Information
1	KM Value [mM]
1	Molecular Weight [Da]
17	Natural Substrates/ Products (Substrates)
26	Organism
6	Protein Variants
1	Purification (Commentary)
1	Reaction
1	Reaction Type
25	Reference
24	Substrates and Products (Substrate)
37	Synonyms

CAS Registry Number

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CAS Registry Number on EC 3.4.22.B19 - YopJ protease

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CAS REGISTRY NUMBER

COMMENTARY

355808-07-0

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