3.4.22.B14: papain-like proteinase 1

This is an abbreviated version, for detailed information about papain-like proteinase 1, go to the full flat file.

Reaction

papain-like proteinase 1 is responsible for cleavages located at the N-terminus of the replicase polyprotein =

Synonyms

C16.001, first papain-like cysteine proteinase, mouse hepatitis virus papain-like proteinase 1, PL1-PRO, PL1pro, PLP-1, PLP1, PLP1 proteinase, PLpro, replicase polyprotein 1a

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B14 papain-like proteinase 1

Temperature Optimum

Temperature Optimum on EC 3.4.22.B14 - papain-like proteinase 1

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TEMPERATURE OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
22
reaction is significantly more efficient at 22C than when carried out at 30C